Ownership Profile

Shareholder Breakdown

Shareholder Holders Value ($MM) % O/S Shares
Institution 198 527.77 105.42 45,286,572
Mutual Fund 369 200.40 32.48 13,910,019
Insider 16 7.22 1.07 460,055

Institutional Shareholder Rotation

Shareholder Holders Value Chg ($MM) % O/S Share Change
Buyers 107 104.80 20.96 9,005,485
Sellers 105 -126.42 22.95 -9,859,449
Net -21.63 1.99 -853,964

Institutional Shareholder Concentration

Value ($MM) % O/S Shares
Total Inst. 534.65 106.42 45,716,527
Top 10 Inst. 317.99 63.87 27,436,883
Top 20 Inst. 412.51 82.85 35,591,689
Top 50 Inst. 494.15 98.99 42,526,577

Institutional Shareholder Style

Holders Value ($MM) % Inst Shares Shares
Growth 55 105.82 21.11 9,069,738
Aggressive Growth 3 5.04 1.01 434,568
Core Growth 41 65.20 12.97 5,570,499
Growth 11 35.59 7.13 3,064,671
Income 5 1.47 0.29 125,342
Income Value 1 1.37 0.27 117,869
Yield 4 0.11 0.02 7,473
Index 25 114.40 22.95 9,857,916
Other 63 280.45 56.01 24,062,599
Broker Dealer 15 14.82 2.98 1,278,261
GARP 17 26.75 5.16 2,216,747
Hedge Fund 29 199.10 39.89 17,134,502
Specialty 1 1.88 0.38 162,518
VC Private Equity 1 37.91 7.61 3,270,571
Value 25 13.41 2.65 1,137,844
Core Value 22 11.48 2.26 971,272
Deep Value 3 1.93 0.39 166,572

Top Holders: Institutional Investor

Holder Shares Held % O/S Share Change Filing Date
RA Capital Management, LP 3,987,560 9.28 3,987,560 9/30/19
BlackRock Institutional Trust Company, N.A. 3,382,162 7.87 77,317 9/30/19
Perceptive Advisors LLC 3,270,571 7.61 -502,011 9/30/19
Scopia Capital Management LP 3,219,898 7.50 -71,414 9/30/19
Macquarie Investment Management 2,685,790 6.25 91,796 9/30/19
The Vanguard Group, Inc. 2,366,696 5.51 174,694 9/30/19
Manulife Investment Management (US) LLC 2,317,362 5.39 206,950 9/30/19
Consonance Capital Management LP 2,314,421 5.39 -1,498,095 9/30/19
State Street Global Advisors (US) 2,152,423 5.01 535,168 9/30/19
Great Point Partners, LLC 1,740,000 4.05 736,400 9/30/19

* Insider values reflect direct beneficial ownership.

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