Ownership Profile

Shareholder Breakdown

Shareholder Holders Value ($MM) % O/S Shares
Institution 193 523.11 102.59 44,072,267
Mutual Fund 384 188.68 32.63 13,913,993
Insider 16 9.35 1.09 466,555

Institutional Shareholder Rotation

Shareholder Holders Value Chg ($MM) % O/S Share Change
Buyers 111 103.36 20.71 8,895,250
Sellers 103 -125.94 22.87 -9,825,024
Net -22.58 2.16 -929,774

Institutional Shareholder Concentration

Value ($MM) % O/S Shares
Total Inst. 533.06 105.70 45,405,892
Top 10 Inst. 317.99 63.87 27,436,883
Top 20 Inst. 409.92 82.33 35,368,557
Top 50 Inst. 491.90 98.28 42,219,500

Institutional Shareholder Style

Holders Value ($MM) % Inst Shares Shares
Growth 53 107.01 21.10 9,062,683
Aggressive Growth 3 5.19 1.00 431,677
Core Growth 40 65.16 12.96 5,568,799
Growth 10 36.65 7.13 3,062,207
Income 5 1.46 0.29 125,546
Income Value 1 1.37 0.27 117,869
Yield 4 0.09 0.02 7,677
Index 24 114.56 22.89 9,831,236
Other 63 274.69 53.23 22,863,418
Broker Dealer 15 12.23 2.46 1,055,129
GARP 16 22.78 4.55 1,953,373
Hedge Fund 29 199.02 38.14 16,385,402
Specialty 1 1.88 0.38 162,518
VC Private Equity 1 37.91 7.61 3,270,571
Sector Specific 1 0.87 0.09 36,425
Value 26 13.45 2.65 1,138,388
Core Value 23 11.52 2.26 971,816
Deep Value 3 1.93 0.39 166,572

Top Holders: Institutional Investor

Holder Shares Held % O/S Share Change Filing Date
RA Capital Management, LLC 3,987,560 9.28 3,987,560 9/30/19
BlackRock Institutional Trust Company, N.A. 3,382,162 7.87 77,317 9/30/19
Perceptive Advisors LLC 3,270,571 7.61 -502,011 9/30/19
Scopia Capital Management LP 3,219,898 7.50 -71,414 9/30/19
Macquarie Investment Management 2,685,790 6.25 91,796 9/30/19
The Vanguard Group, Inc. 2,366,696 5.51 174,694 9/30/19
Manulife Investment Management (US) LLC 2,317,362 5.39 206,950 9/30/19
Consonance Capital Management LP 2,314,421 5.39 -1,498,095 9/30/19
State Street Global Advisors (US) 2,152,423 5.01 535,168 9/30/19
Great Point Partners, LLC 1,740,000 4.05 736,400 9/30/19

* Insider values reflect direct beneficial ownership.

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